Projects

Recruitment and phenotyping of patients, documentation in web-based register, enabling natural history and controlled clinical studies.

University of München

Developing a simple and highly sensitive assay to quantify the five mitochondrial oxidative phosphorylation complexes from patient samples, and screening the cohort of patients of the consortium by the novel protocol.

University of Frankfurt

Establishing the analysis of abnormal mitochondrial fission and fusion in human cells as a new assay to follow and diagnose mitochondrial cytopathies.

University of Tübingen

Providing innovative and cutting edge technology for molecular diagnosis of mitochondrial disorders.

Technische Universität München

Using a The probabilistic Bayesian network approach towards the diagnose of mitochondrial disease will quantitatively delineate and specify subsets of disease phenotypes, thus facilitating detection of the basic genetic defects.

Charité Berlin

Testing pharmacological approaches in cell culture

Technical University of München

To identify the mechanisms behind and strategies against the propagation of mtDNA mutations.

University of Jena

To collect biological materials and make them available to network partners

Technische Universität München

To make myoblast cultures available to network partners

University of München

CMR-based diagnosis of cardiac involvement in patients with mitochondrial myopathy

Robert-Bosch-Krankenhaus Stuttgart